ENGLAND, UK

Sandwich Lab (Analytical Sciences)

Founded in 2012

Based at Discovery Park in Sandwich, Kent, our Sandwich facility is a dedicated materials science and analytical development lab. 

Lab Description

The Sandwich lab offers you tailored services and partnership to navigate your pharmaceutical development journey from discovery to commercial manufacture.

Resolian’s scientists offer extensive expertise in analytical and materials science solutions to support and troubleshoot new and existing products. 

Resolian Analytical Sciences Sandwich
Discovery Park, Ramsgate Rd, Sandwich CT13 9FF

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Services Provided

Materials Science Solutions: Dedicated characterization services to enable better understanding of the solid state and physical properties of your materials.

Analytical Solutions: Bespoke, phase-appropriate analytical methods for identification, characterization and testing of your material to underpin chemistry, manufacturing and controls (CMC).

Foreign Matter Analysis: Forensic analysis of contamination to determine its identity and source, and to support root cause investigations and remediation for more robust processes.

Supporting a Wide Range of Industries: Our experience spans across multiple disciplines and we provide solutions to suit the individual challenges of industries:

  • Pharmaceutical & Biopharmaceutical
  • Veterinary Medicine & Animal Nutrition
  • Medical Devices & Design
  • Personal Care and Cosmetics
  • Agrochemicals & Agriculture
  • Food & Beverage
  • Chemicals & Standards
  • Catalysts
  • Electronic Cigarettes

Materials Characterization Instruments

Solid Form Characterization

  • Bruker D2 PXRD
  • Bruker D8 Advance PXRD
  • Perkin Elmer Spectrum Two FTIR spectrometer
  • Perkin Elmer Spotlight 200i FTIR microscope
  • Perkin Elmer DSC8000
  • TGA (TA Instruments TGA550)

Particle Size, Count, Shape

  • Malvern Mastersizer 3000 (dry and wet dispersion)
  • Sympatec HELOS KF (dry, T4.1 module)
  • Sympatec HELOS KR (dry and wet dispersion)
  • Sympatec QICPIC
  • Beckman Coulter 9703+ HIAC

Light and Electron Microscopy

  • Nikon Ni-U Eclipse with camera and NIS Elements-D software
  • Nikon SMZ745T with camera and NIS Elements-D software
  • Olympus BX51 with camera
  • Olympus SZX12 with camera
  • Mettler Toledo FP82HT Hot Stage and FP90 Central Processor (for hot stage microscopy)
  • Carl Zeiss Sigma FE-SEM

Physicochemical Properties

  • SMS iGC-SEA
  • Micrometrics TriStar 3000
  • Micrometrics TriStar 3020
  • SMS DVS Advantage One
  • SMS DVS Resolution

Density

  • Varian Tapped Density Analyzer
  • Helium Pycnometer (Accupyc II 1340)

Elemental Analysis (SEM-EDX)

  • Thermo Ultradry EDX with NSS software
  • EDAX (Ametek) Octane Elect Plus EDX with Apex software

Separation Science and 
Wet Chemistry Instruments

LC Instruments

  • Waters Acquity UPLC with Waters G2-XS Q-TOF-MS
  • Waters Acquity UPLC with QDa MS and DAD
  • Agilent 1100 HPLC with DAD
  • Agilent 1100 HPLC with VWD
  • Agilent 1260 HPLC with DAD and FLD

Water Content, Viscosity, pH

  • Metrohm Karl Fisher Titrino 870KF (volumetric)
  • Mettler Toledo pH meters and ion electrodes
  • Brookfield DV2T-RV Viscometer

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Zhiyang Zhao, Ph.D.

Chief Scientific Officer

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Zhiyang Zhao, Ph.D., serves as Chief Scientific Officer (CSO) at Resolian. Dr. Zhao has over 30 years of pharmaceutical industry experience with special focus on drug metabolism and bioanalysis of small and large molecules in drug discovery and development. Dr. Zhao has previously held positions at Pfizer, GlaxoSmithKline, and Amgen. Before joining Resolian in 2015, Dr. Zhao served as Site Director of Preclinical Research at Amgen in Cambridge, Massachusetts, for over a decade. 

Currently, Dr. Zhao serves as an Adjunct Professor at the Eshelman School of Pharmacy of the University of North Carolina at Chapel Hill, North Carolina, and as Editor-in-Chief of Drug Metabolism & Bioanalysis Letters, a journal by Bentham Science, which publishes in all areas of drug metabolism and bioanalysis. Dr. Zhao received his Ph.D. degree in Medicinal Chemistry from Virginia Polytechnic and State University (popularly known as Virginia Tech) in Blacksburg, Virginia. 

Patrick Bennett

Chief Executive Officer

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Patrick Bennett has over 35 years of experience in pharmaceutical analysis and laboratory management. Now Chief Business Officer at Resolian, Patrick’s experience includes the roles of Strategic Marketing Director for Pharma with Thermo Fisher Scientific, LabCorp, and Vice President of Strategy and Development with PPD. 

Patrick earned a B.S. degree in Toxicology and a M.S. degree in Pharmacology from the College of Pharmacy and Allied Health at St. John’s University and an M.B.A in International Marketing from the Martin J. Whitman School of Management at Syracuse University.