Immunogenicity
Developing, validating and implementing anti-drug antibody (ADA) immunogenicity and neutralizing antibody (nAb) assays.
Services
- Assay development, validation and sample analysis
- Pre-clinical and clinical immunogenicity and nAb assays
- Ligand binding and cell-based assays
- Acid dissociation
- ACE
- SPEAD
- Isotyping assays
Therapeutic Modalities
- Monoclonal antibodies (mAbs)
- Antibody fragments (Fab, nanobody, domain Abs)
- Antibody drug conjugates (ADCs)
- Proteins
- Peptides
- Bispecifics
- Biosimilars
- AAVs, gene therapy
Technologies
- ELISA (absorbance, luminescence, fluorescence)
- GyroLab xPand, xPlore™
- Quanterix (HDX Simoa)
- Electrochemiluminescence (MSD Sector Imager 6000, QuickPlex)
- Luminex (Magpix, Flexmap 3D)
- Flow cytometry (Beckman Coulter CytoFLEX)
- qPCR (QuantStudio™ 7) and Hybridization ELISA
- Luminex Flexmap 3D
- Protein Simple Ella
- Thermo Scientific NanoDrop
- Hamilton STAR Robotics
